Founded in 1962, the school was formerly known as Jianlian Middle School, which was a joint venture between the Federation of Industry and Commerce and the Democratic Construction Association. In 1965, it was renamed "Hongwei Middle School", and in 1969, it was changed to a public school and officially renamed "Guangzhou No. 97 Middle School".

The school's philosophy is "to lay the foundation for students' healthy life", so the school's learning atmosphere is more pleasant, and the first and second years of junior high school pay great attention to the cultivation of literacy and ability, and only after entering the third year of junior high school will they put their energy into preparing for the entrance examination. Many people think that in this mode of schooling, students' grades will be more average. In fact, from 2004 to 2012, 97 Middle School won the first prize of comprehensive evaluation of the work of junior high school graduating classes in Haizhu District for 9 consecutive times; From 2005 to 2012, the total average score of the high school entrance examination ranked first among public schools in Haizhu District for 8 consecutive years; In 2014, the number of students with a score of 700 or above in the high school entrance examination accounted for 35.7% of the whole level, ranking first among public schools in Haizhu District; In 2016, the results of the middle school entrance examination reached a new high, and the total score of the high school entrance examination in Haizhu District came from 97 middle schools, the number of candidates with a score of more than 700 accounted for 42% of the candidates in the school, and more than 70% of the junior high school graduates went to schools above the provincial level. It can be said that since the No. 6 Middle School canceled the junior high school public school, No. 97 Middle School has become the leader in the public middle school in Haizhu District.

The brand strong class is a feature that 97 Middle School strives to create, and each class has its own brand characteristics, such as science and technology brand class, international ecological class, etc. At the same time, it will give full play to the function of the "Thumb Parent School" as a municipal parent demonstration school, strengthen the connection between home and school, and let parents and children grow together. In terms of teachers, the teachers of 97 Middle School are young and energetic. Nearly 40 teachers have been rated as provincial, municipal, and district famous teachers, as well as serving as special committees, teaching and research associations and other positions. There are 57 special teachers in 97 and 50 master's and master's degrees in education.

97 Middle School attaches great importance to students' ability and literacy. Through the holding of art festivals, sports meetings, discipline and cultural festivals, as well as the host district environmental protection science and technology festival, the comprehensive quality of students is cultivated. As one of the first batch of art key base schools in Guangzhou, 97 Middle School students have won many awards in various competitions such as science and technology, art, and sports, including the first, second, and third prizes in the National Youth Radio Communication Competition, and the top three in national, provincial and municipal robot competitions.

At present, 97 Middle School has three campuses: Dongxiaonan Campus, Jinbi Garden Campus and Jiangnan Xinyuan Campus. Its junior high school is located in Jiangnan Xinyuan Campus, covering an area of 12,500 square meters, with reasonable campus layout and advanced teaching facilities. In addition, the school also has an indoor basketball hall, a 400-person lecture hall, a 700-square-meter dance studio, a sunshine book bar, a maker studio and other activity venues.