Former name: Wu Tai Gankang, compound aminophenamine tablets, an antiviral cold medicine brand under Wu Tai Pharmaceutical Group, and a leading brand in the domestic cold medicine market
Gankang is a product produced by Jilin Wutai Gankang Pharmaceutical Co., Ltd. It is mainly suitable for relieving fever, headache, limb tenderness, sneezing, and other symptoms caused by common cold and influenza.
Compound aminophenamine tablets (Gankang) Common name: compound aminophenamine tablets
Former name: Wu Taigankang
This product is a compound preparation, and its components are: each tablet contains 0.25g of acetaminophen, 0.1g of amantadine hydrochloride, 15mg of caffeine, 10mg of artificial bezoar, and 2mg of chlorpheniramine maleate.
Characters:This product is a light yellow flake.
Pharmacology and toxicology
Acetaminophen in this product has antipyretic and analgesic effect, and its mechanism of action is to produce peripheral vasodilation by inhibiting the synthesis and release of prostaglandins, the central prostaglandin (PGE2) of the hypothalamus thermoregulation, causing sweating to achieve antipyretic effect, and at the same time, it can inhibit the effect of bradykinin, etc., and increase the pain threshold to produce analgesic effect. Chlorpheniramine maleate is an antihistamine that can competitively block H1 receptors to produce anti-allergic effects, and can also eliminate or alleviate nasal congestion, sneezing, runny nose and various allergic symptoms, and has a sedative effect. Amantadine has anti-influenza A virus effects, and the rest of the components have antipyretic, analgesic, anti-inflammatory, anti-allergic and other effects.
Indications
It is suitable for relieving fever, headache, limb tenderness, sneezing, runny nose, nasal congestion, sore throat and other symptoms caused by common cold and influenza.
Dosage
Take orally. Adults take 1 tablet once, 2 times a day.
Adverse effects
1. Occasional rash, nausea, vomiting, sweating, abdominal pain, anorexia and paleness, etc., individual patients have drowsiness or mild dizziness after the initial dose, and the symptoms disappear after stopping the drug.
2. Occasional hyperhemoglobinemia and cyanosis.
3. Sometimes it can cause hallucinations and mental disorders, and occasionally there are slurred speech and involuntary eye movements, which are generally manifestations of overexcitation or poisoning of the central nervous system.
4. For elderly patients, it can cause dysuria, fainting, and often cause orthostatic hypotension.
5. Occasional leukopenia.
6. The more stubborn adverse reactions are: inability to concentrate, dizziness, irritability, anorexia, nervousness, purple-red reticular spots or reticular blue spots on the skin, sleep disorders, nightmares, etc. Headache, blurred vision, dry mouth, nose and throat, constipation, fatigue and weakness are rare.
7. Long-term treatment can show swelling of the lower limbs.
taboo
1. Those who are allergic to the components of this product are prohibited.
2. Patients with active peptic ulcer are prohibited.
3. Pregnant and lactating women are prohibited.
4. Children under 1 year old are prohibited.
Precautions
1. Avoid driving motor vehicles, operating machinery and working at heights after taking this product.
2. Drinking alcohol while taking this product will increase the adverse reactions of this product.
Use with caution in the following situations:
1. Patients with liver and kidney insufficiency;
2. History of cerebrovascular disease, history of recurrent eczema-like rash, peripheral edema, congestive heart failure, psychosis or severe neurosis, and history of epilepsy
4. Cross-allergic reaction For a small number of patients with asthma who are allergic to aspirin, mild bronchospasmodic reactions may occur after taking it.
5. It is not advisable to use a large amount or long-term medication to prevent damage to the hematopoietic system and liver and kidney function.
6. Interference with laboratory examinations: Glucose oxidase/peroxidase method can be used to determine blood glucose to obtain falsely low values; Determination of serum uric acid by phosphotungstic acid method can obtain falsely high values; Qualitative screening test of urine 5-hydroxyindole acetic acid with nitrosonaphthol reagent can obtain false-positive results, and the quantification is not affected; One large dose or a long-term low dose can increase prothrombin time, serum bilirubin, serum lactate dehydrogenase, and serum transferase.
7. It is forbidden to use when the properties of the drug are changed.
8. Medication for pregnant and lactating women. Amantadine, acetaminophen, and artificial bezoar in this product can all pass through the placenta, which is toxic to the embryo and can be teratatical, and may cause adverse effects on the fetus; Except for artificial bezoars, they can be secreted through breast milk, so pregnant and lactating women are prohibited.
9. Children's medication. Not for children under 1 year of age.
10. Medication for elderly patients. Use with caution or reduce the dosage appropriately.
other
1. Storage: Sealed and stored in a cool and dry place.
2. Packing: 12 tablets per box; Aluminum foil packaging.
3. Validity period: 36 months
4. Approval number: national medicine quasi-word H22026193
5, the manufacturer: Jilin Province Wu Taigankang Pharmaceutical Co., Ltd
