Founded in 1958, the Guangzhou Institute of Dermatology Prevention and Treatment is a specialized hospital under the Guangzhou Municipal Health and Family Planning Commission, a key clinical specialty of skin in Guangdong Province, and one of the only seven standardized monitoring hospitals for venereal diseases in the country. In 2014, the Institute of Dermatology and the Department of Dermatology and Venereology of Guangzhou Medical University settled in the institute, which is an important teaching base for dermatology and venereology in Guangzhou. Its venereal disease testing and syphilis specialties are in the leading position in the province, and they also have a certain reputation in China. As the core unit of STD diagnosis and treatment in Guangzhou, the doctors employed by the STD Prevention and Control Department of the institute have rich experience in STD research and clinical practice. Deputy Director Ye Xingdong is a graduate of Sun Yat-sen Medical University with a master's degree, the secretary of the Guangdong Dermatology and Venereology Branch of the Chinese Medical Doctor Association, and a member of the Guangdong Dermatology and Venereology Branch of the Chinese Medical Association. He has extensive experience in the diagnosis and treatment of sexually transmitted diseases. Chief Physician Yang Ridong has more than 20 years of experience in the diagnosis and treatment of common and difficult skin diseases and venereal diseases, especially in the diagnosis and treatment of sexually transmitted diseases (mainly syphilis, herpes, genital warts and non-gonococcal urethritis), especially in the clinical diagnosis and treatment of syphilis and post-STD prostatitis. Syphilis is one of the most well-known sexually transmitted diseases, and the causative agent is Treponemia pallidum (TP), in addition to sexual transmission, it can also be transmitted through blood and mother-to-child transmission, and is divided into early syphilis and late syphilis for more than 2 years according to the course of the disease, which will spread to the cardiovascular, nervous, skin and mucous membranes, etc., causing damage. Parenteral administration of penicillin G is the first choice for the treatment of syphilis in all stages, and this treatment regimen has been verified by decades of clinical trials and observational studies, but a skin test is required before injection of penicillin, and when penicillin kills treponema pallidum after injection, the body absorbs a large amount of heterosexual proteins and endotoxins, and there may be high fever, jaundice and other reactions, so do not self-inject penicillin. In addition, in recent years, there have been cases of "false positive" and "false negative" syphilis testing, mainly because although there are many syphilis detection methods, such as the common RPR (rapid plasma reagin ring card test), TRUST (toluidine red unheated serum test) and TPPA (treponema pallidum particle agglutination test) for Treponema pallidum, there is no perfect testing program, resulting in screening and diagnosis errors, which brings pressure to doctors and patients. It is particularly important for more authoritative STD hospitals to conduct testing. In addition to skilled physicians, the Municipal Dermatology Prevention Institute has formed a unique examination and treatment plan in many years of diagnosis and treatment, and has advantages in related fields, including painless lumbar puncture neurosyphilis detection, diagnosis and treatment of post-STD prostatitis, and photodynamic therapy. Among them, the institute is currently the only medical institution in the province that can conduct comprehensive syphilis-related testing of cerebrospinal fluid to confirm or rule out neurosyphilis, and has carried out such testing for nearly 20 years; The patient had no pain when the cerebrospinal fluid was removed during lumbar puncture, and there was no serious adverse reaction after surgery, and there was no need to be hospitalized, and the patient had a good experience. Guangzhou Leather Prevention Institute currently has two outpatient departments of Zhongshan 4th Road and Hengfu Road, Zhongshan 4th Road Outpatient Department is located in the center of the city, plus the history is longer, the environment is more cramped, and there are often crowded; The area of Hengfu Road is slightly larger and the environment is relatively new, but there are still many people registered every day. It is recommended that patients make an appointment on the online platform as much as possible to avoid delaying the consultation time. The STD Prevention and Treatment Department of Hengfu Road Campus is located on the 4th floor, and the number of waiting rooms is usually small, and each clinic is independent of each other and has good privacy.